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Mingqing Xu

Special Researcher

  • Tel: +86-021-62933378 Extension 8002
  • Email: mingqingxu@sjtu.edu.cn
  • Address: Room 212, Genomics Building, 1954 Huashan Road, Xuhui ,Shanghai 200030, China
  • Lab Web: http://www.bio-x.cn
  • Dr. Xu’s main research directions include: 1) statistical inference and data mining of multi-omics biomedical big data; 2) molecular genetic basis of human diseases; 3) system biology and synthetic biology; 4) single molecule manipulation and nanobiotechnolog.

Selected Publications

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    Xirui Wang, Xianting Jiao, Bin Wang, Juan Li, Fan Yang, Lishan Zhang, Lei Xu, Mingqing Xu*, Xiaodan Yu*. Effects of circulating vitamin D levels on emotion, behavior and attention: A cross-sectional study in preschool children with follow-up behavior experiments in juvenile mice. Journal of Affective Disorders. In Press

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    Chen J#, Zhao X#, Cui L#, He G, Wang X, Wang F, Duan S, He L, Li Q, Zhang F, Yu X*, Xu M*. Genetic regulatory subnetworks and key regulating genes in rat hippocampus perturbed by prenatal malnutrition: implications for major brain disorders. Aging (Albany NY). 2020 May 11;12(9):8434-8458. doi: 10.18632/aging.103150.

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    Jin G#, Xu M#, Zou M, Duan S. The Processing, Gene Regulation, Biological Functions, and Clinical Relevance of N4-Acetylcytidine on RNA: A Systematic Review. Mol Ther Nucleic Acids. 2020 Feb 8;20:13-24. doi: 10.1016/j.omtn.2020.01.037. 

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    Liu M, Li F, Yan H, Wang K, Ma Y; Alzheimer’s Disease Neuroimaging Initiative, Shen L, Xu M*. A multi-model deep convolutional neural network for automatic hippocampus segmentation and classification in Alzheimer's disease. Neuroimage. 2020 Mar;208:116459. doi: 10.1016/j.neuroimage.2019.116459.

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    Li H#, Wang X#, Lu X, Zhu H, Li S, Duan S, Zhao X, Zhang F, Alterovitz G, Wang F, Li Q, Tian XL*, Xu M*. Co-expression network analysis identified hub genes critical to triglyceride and free fatty acid metabolism as key regulators of age-related vascular dysfunction in mice. Aging (Albany NY). 2019 Sep 12;11(18):7620-7638. doi: 10.18632/aging.102275.

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    Zheng S, Zhao T, Yuan S, Yang L, Ding J, Cui L*, Xu M*. Immunodeficiency Promotes Adaptive Alterations of Host Gut Microbiome: An Observational Metagenomic Study in Mice. Front Microbiol. 2019 Nov 1;10:2415. doi: 10.3389/fmicb.2019.02415.

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    Jiang L, Wang K, Lo K, Zhong Y, Yang A, Fang X, Akezhuoli H, Song Z, Chen L, An P, Xu M*, Min J*, Wang F*. Sex-Specific Association of Circulating Ferritin Level and Risk of Type 2 Diabetes: A Dose-Response Meta-Analysis of Prospective Studies. J Clin Endocrinol Metab. 2019 Oct 1;104(10):4539-4551. doi: 10.1210/jc.2019-00495.PMID: 31074789

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