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Yan Feng

Distinguished Professor

  • Tel: +86-021-34207189
  • Email: yfeng2009@sjtu.edu.cn

Selected Publications

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    Zhuang Y, Yang GY, Chen X, Liu Q, Zhang X, Deng Z, Feng Y*.Biosynthesis ofplant-derived ginsenoside Rh2 in yeast via repurposing a key promiscuous  microbial enzyme. Metab Eng. 2017 Jul; 42:25-32.

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    Hoque MA, Zhang Y, Chen L, Yang G, Khatun MA, Chen H, Hao L, Feng Y*.Stepwise Loop Insertion Strategy for Active Site Remodeling to Generate Novel Enzyme Functions. ACS Chem Biol. 2017 May 19;12(5):1188-1193.

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    Han YB, Chen LQ, Li Z, Tan YM, Feng Y, Yang GY.Structural Insights into the Broad Substrate Specificity of a Novel Endoglycoceramidase I Belonging to a New Subfamily of GH5 Glycosidases. J Biol Chem. 2017 Mar 24; 292(12): 4789-4800.

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    Huang J, Xie DF, Feng Y*.Engineering thermostable (R)-selective amine transaminase from Aspergillus terreus through in silico design employing B-factor and folding free energy calculations. Biochem Biophys Res Commun. 2017 Jan 29; 483(1):397-402.

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    Yu S, Zhou X, Li F, Xu C, Zheng F, Li J, Zhao H, Dai Y, Liu S, Feng Y*. Microbial transformation of ginsenoside Rb1, Re and Rg1 and its contribution to the improved anti-inflammatory activity of ginseng. Sci Rep, 2017 Mar 10; 7(1): 138.

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    Jiang H, Xia XX, Feng Y, Zhong JJ, Qian ZG. Development of a robust system for high-throughput colorimetric assay of diverse amino acid decarboxylases. Process Biochem. 2017 Sep, 60:27-34.

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    Ma F, Xie Y, Luo M, Wang S, Hu Y, Liu Y, Feng Y, Yang GY. Sequence homolog-based molecular engineering for shifting the enzymatic pH optimum. Synthe Syst Biotechnol, 2016 Oct 4; 1(3): 195-206.

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    Zhang XF, Yang GY, Zhang Y, Xie Y, Withers SG, Feng Y*. A general and efficient strategy for generating the stable enzymes. Sci Rep. 2016 Sep 26;6:33797.

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    Zhang Y, An J, Yang G, Zhang X, Xie Y, Chen L, Feng Y*.Structure features of GH10 xylanase from Caldicellulosiruptor bescii: implication for its thermophilic adaption and substrate binding preference. Acta Biochim Biophys Sin (Shanghai). 2016 Oct;48(10):948-957. 

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    Ma F, Fischer M, Han Y, Withers SG, Feng Y, Yang GY. Substrate Engineering Enabling Fluorescence Droplet Entrapment for IVC-FACS-Based Ultrahigh-Throughput Screening. Anal Chem. 2016 Sep 6;88(17):8587-95.