Yi Xiao

Special Researcher/Tenure-track Associate Professor

  • Tel: +86-021-34208601
  • Email:
  • Address: Xitong Building (Room C404), 800 Dongchuan RD. Minhang District, Shanghai, China

Education and Research Experience

  • 2017-Current, Associate Professor, Shanghai Jiao Tong University
  • 2010-2016, Research Scientist and Postdoc,Washington University in St. Louis, USA
  • 2008-2010, Postdoc, South China Sea Institute of Oceanology, Chinese Academy of Sciences, China
  • 2019-Current, the Editorial Board of Applied and Environmental Microbiology

Research Interests

Biotechnology and Biosynthesis

Development of CRISPR-associated tools for genome editing and regulation

Biosynthesizing high-value bioproducts via cell factories

Selected Publications

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    Mingtao Zhao, Xulin Hong, Abdullah, Rulin Yao, Yi Xiao*. Rapid biosynthesis of phenolic glycosides and their derivatives from biomass-derived hydroxycinnamates. Green Chemistry, 23, 838-847


    Ruilian Yao#, Di Liu#, Xiao Jia, Yuan Zheng, Wei Liu, Yi Xiao*. CRISPR-Cas9/Cas12a biotechnology and application in bacteria. Synthetic and Systems Biotechnology. 3(3):135-149


    Mingtao Zhao, Yankai Tao, Xiaofeng Wu, Yi Xiao*. One-pot efficient biosynthesis of 4-hydroxyphenylacetic acid and its analogues from lignin-related p-coumaric and ferulic acids. ACS Sustainable Chemistry & Engineering, (10.1021/acssuschemeng.1c00993)


    Yi Xiao, Shaojie Wang, Sarah Rommelfanger, Andrea Balassy, Carlos Barba-Ostria, Pengfei Gu, Jonathan M. Galazka, Fuzhong Zhang*.  Developing a Cas9-based tool to engineer native plasmids in Synechocystis sp. PCC 6803. Biotechnology and Bioengineering 115(9):2305-2314.


    Yi Xiao, Christopher H. Bowen, Di Liu, Fuzhong Zhang.  Exploiting nongenetic cell-to-cell variation for enhanced biosynthesis. Nature Chemical Biology 12, 339–344

Teaching Experiences

  • Fundamentals of natural science
  • CRISPR gene editing
  • English writing 
  • National 1000 Youth Talents Program 2018
  • National Key R&D Program of China 2019/2018
  • National Natural Science Foundation of China 2019
  • Science and Technology Commission of Shanghai Municipality 2018

Selected Grants